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1

The immunopathology of sepsis and potential therapeutic targets

van der Poll, Tom, van de Veerdonk, Frank L., Scicluna, Brendon P., Netea, Mihai G.

Journal:

Nature Reviews Immunology

Year:

2017

Language:

english

File:

PDF, 742 KB

english, 2017

2

Immunomodulation by macrolides: therapeutic potential for critical care

Reijnders, Tom D Y, Saris, Anno, Schultz, Marcus J, van der Poll, Tom

Journal:

The Lancet Respiratory Medicine

Year:

2020

File:

PDF, 826 KB

2020

3

Two-Way Interactions Between Inflammation and Coagulation

Marcel Levi, Tom van der Poll

Journal:

Trends in Cardiovascular Medicine

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

4

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

Tom van der Poll, Steven M Opal

Journal:

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

5

Plasminogen Activator and Plasminogen Activator Inhibitor I Release during Experimental Endotoxaemia in Chimpanzees: Effect of Interventions in the Cytokine and Coagulation Cascades

Biemond, Bart J., Levi, Marcel, Ten Cate, Hugo, Van Der Poll, Tom, Büller, Harry R., Hack, C. Erik, Ten Cate, Jan W.

Journal:

Clinical Science

Year:

1995

Language:

english

File:

PDF, 652 KB

english, 1995

6

Coagulation and sepsis

Levi, Marcel, van der Poll, Tom

Journal:

Thrombosis Research

Year:

2017

Language:

english

File:

PDF, 444 KB

english, 2017

7

1374. Integrated Safety Summary of Omadacycline: A Novel Aminomethylcycline Antibiotic

Opal, Steven, File, Thomas M, Van Der Poll, Tom, McGovern, Paul, Tzanis, Evan, Chitra, Surya

Journal:

Open Forum Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 599 KB

english, 2018

8

Coinfection with Borrelia burgdorferi sensu stricto and Borrelia garinii alters the course of murine Lyme borreliosis

Joppe W.R. Hovius, Xin Li, Nandhini Ramamoorthi, Alje P. Van Dam, Stephen W. Barthold, Tom Van Der Poll, Peter Speelman, Erol Fikrig

Journal:

FEMS Immunology & Medical Microbiology

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

9

The Systemic Pro-Inflammatory Response in Sepsis

de Jong, Hanna Katrien, van der Poll, Tom, Wiersinga, Willem Joost

Journal:

Journal of Innate Immunity

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

10

Host–pathogen interactions in sepsis

Tom van der Poll, Steven M Opal

Journal:

The Lancet Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008

11

The intestinal microbiota and host immune interactions in the critically ill

Schuijt, Tim J., van der Poll, Tom, de Vos, Willem M., Wiersinga, W. Joost

Journal:

Trends in Microbiology

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

12

Severe Sepsis and Septic Shock

Angus, Derek C., van der Poll, Tom

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 655 KB

english, 2013

13

Methodological challenges in monitoring new treatments for rare diseases: lessons from the cryopyrin-associated periodic syndrome registry

Tilson, Hugh, Primatesta, Paola, Kim, Dennis, Rauer, Barbara, Hawkins, Philip N, Hoffman, Hal M, Kuemmerle-Deschner, Jasmin, van der Poll, Tom, Walker, Ulrich A

Journal:

Orphanet Journal of Rare Diseases

Year:

2013

Language:

english

File:

PDF, 371 KB

english, 2013

14

Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia

Hommes, Tijmen J, Hoogendijk, Arie J, Dessing, Mark C, van't Veer, Cornelis, Florquin, Sandrine, Colonna, Marco, de Vos, Alex F, van der Poll, Tom

Journal:

The Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 704 KB

english, 2014

15

Role of CD14 in lung inflammation and infection

Adam Anas,Tom van der Poll,F de Vos Alex

Journal:

Critical Care (BioMed Central)

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

16

The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion

Dessing, Mark C, Tammaro, Alessandra, Pulskens, Wilco P, Teske, Gwendoline J, Butter, Loes M, Claessen, Nike, van Eijk, Marco, van der Poll, Tom, Vogl, Thomas, Roth, Johannes, Florquin, Sandrine, Leem

Journal:

Kidney International

Year:

2015

Language:

english

File:

PDF, 2.12 MB

english, 2015

17

Differential Effects of Anti-cytokine Treatment on Bronchoalveolar Hemostasis in Endotoxemic Chimpanzees

LEVI, MARCEL, van der POLL, TOM, ten CATE, HUGO, KUIPERS, BART, BIEMOND, BART J., JANSEN, HENK M., ten CATE, JAN WOUTER

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1998

Language:

english

File:

PDF, 93 KB

english, 1998

18

The Cholinergic Anti‐Inflammatory Pathway Regulates the Host Response during Septic Peritonitis

van Westerloo, David J., Giebelen, Ilona A. J., Florquin, Sandrine, Daalhuisen, Joost, Bruno, Marco J., de Vos, Alex F., Tracey, Kevin J., van der Poll, Tom

Journal:

The Journal of Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 1.66 MB

english, 2005

19

A Short Contemporary History of Disseminated Intravascular Coagulation

Levi, Marcel, van der Poll, Tom

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2014

Language:

english

File:

PDF, 141 KB

english, 2014

20

Sepsis—The Final Common Pathway to Death From Multiple Organ Failure in Infection

Kissoon, Niranjan, Daniels, Ron, van der Poll, Tom, Finfer, Simon, Reinhart, Konrad

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 354 KB

english, 2016

21

Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia

Levi, Marcel, Schultz, Marcus J., Rijneveld, Anita W., van der Poll, Tom

Journal:

Critical Care Medicine

Year:

2003

Language:

english

File:

PDF, 220 KB

english, 2003

22

Impact of HIV infection on the haemostatic response during sepsis and malaria

Huson, Michaëla A. M., Kalkman, Rachel, Hoogendijk, Arie J., Alabi, Abraham S., van ‘t Veer, Cornelis, Grobusch, Martin P., Meijers, Joost C. M., van der Poll, Tom

Journal:

British Journal of Haematology

Year:

2016

Language:

english

File:

PDF, 311 KB

english, 2016

23

Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)

Wiersinga, Willem Joost, Veer, Cornelis van’t, van den Pangaart, Petra S., Dondorp, Arjen M., Day, Nicholas P., Peacock, Sharon J., van der Poll, Tom

Journal:

Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 523 KB

english, 2009

24

Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi

Huson, Michaëla A. M., Katete, Chawezi, Chunda, Lilian, Ngoma, Jonathan, Wallrauch, Claudia, Heller, Tom, van der Poll, Tom, Grobusch, Martin P.

Journal:

Year:

2017

Language:

english

File:

PDF, 520 KB

english, 2017

25

Biomarkers in Sepsis

van Engelen, Tjitske S.R., Wiersinga, Willem Joost, Scicluna, Brendon P., van der Poll, Tom

Journal:

Critical Care Clinics

Year:

2017

Language:

english

File:

PDF, 986 KB

english, 2017

26

Validation of a Novel Molecular Host Response Assay to Diagnose Infection in Hospitalized Patients Admitted to the ICU With Acute Respiratory Failure

Koster-Brouwer, Maria E., Verboom, Diana M., Scicluna, Brendon P., van de Groep, Kirsten, Frencken, Jos F., Janssen, Davy, Schuurman, Rob, Schultz, Marcus J., van der Poll, Tom, Bonten, Marc J.M., Cre

Journal:

Critical Care Medicine

Year:

2018

Language:

english

File:

PDF, 330 KB

english, 2018

27

Platelet Activation and Endothelial Cell Dysfunction

van der Poll, Tom, Parker, Robert I.

Journal:

Critical Care Clinics

Year:

2020

Language:

english

File:

PDF, 1.91 MB

english, 2020

28

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

Marjolein A. van Maanen, Maria C. Lebre, Tom van der Poll, Gregory J. LaRosa, Daniel Elbaum, Margriet J. Vervoordeldonk, Paul P. Tak

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 255 KB

english, 2009

29

Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcuspneumoniae infection

Estella A. Koppel, Catharina W. Wieland, Venice C. M. van den Berg, Manja Litjens, Sandrine Florquin, Yvette van Kooyk, Tom van der Poll, Teunis B. H. Geijtenbeek

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

30

Endogenous interferon γ protects against cholestatic liver injury in mice

Miguel E. Sewnath, Tom Van Der Poll, Cornelis J. F. Van Noorden, Fiebo J. W. Ten Kate, Dirk J. Gouma

Journal:

Year:

2002

Language:

english

File:

PDF, 1.25 MB

english, 2002

31

In situ investigation of the chemical composition of ceroid in human atherosclerosis by Raman spectroscopy

Sweder W. E. van de Poll, Tom C. Bakker Schut, Arnoud van der Laarse, Gerwin J. Puppels

Journal:

Journal of Raman Spectroscopy

Year:

2002

Language:

english

File:

PDF, 390 KB

english, 2002

32

Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis

Catharina W. Wieland, Estella A. Koppel, Jeroen den Dunnen, Sandrine Florquin, Andrew N.J. McKenzie, Yvette van Kooyk, Tom van der Poll, Teunis B.H. Geijtenbeek

Journal:

Microbes and Infection

Year:

2007

Language:

english

File:

PDF, 899 KB

english, 2007

33

Gene-expression profiles in murine melioidosis

W. Joost Wiersinga, Mark C. Dessing, Tom van der Poll

Journal:

Microbes and Infection

Year:

2008

Language:

english

File:

PDF, 747 KB

english, 2008

34

ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis

Catharina W. Wieland, Gerritje J.W. van der Windt, Sandrine Florquin, Andrew N.J. McKenzie, Tom van der Poll

Journal:

Microbes and Infection

Year:

2009

Language:

english

File:

PDF, 429 KB

english, 2009

35

CD14 plays a limited role during influenza A virus infection in vivo

Mark C. Dessing, Koenraad F. van der Sluijs, Sandrine Florquin, Tom van der Poll

Journal:

Immunology Letters

Year:

2007

Language:

english

File:

PDF, 762 KB

english, 2007

36

Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract

Catharina W. Wieland, Sandrine Florquin, Jennie M. Pater, Sebastiaan Weijer, Tom van der Poll

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 746 KB

english, 2006

37

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus

Koenraad F. van der Sluijs, Leontine van Elden, Monique Nijhuis, Rob Schuurman, Sandrine Florquin, Henk M. Jansen, René Lutter, Tom van der Poll

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 367 KB

english, 2003

38

Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis

Sebastiaan Weijer, Jaklien C. Leemans, Sandrine Florquin, Takao Shimizu, Satoshi Ishii, Tom Van Der Poll

Journal:

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

39

Pharmacokinetic-pharmacodynamic modeling of the inhibitory effect of erythromycin on tumour necrosis factor-α and interleukin-6 production

Henk-Jan Guchelaar, Marc J. Schultz, Tom Van Der Poll, Richard P. Koopmans

Journal:

Fundamental & Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

40

Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia

Florquin, Sandrine, Van Den Berg, Jose G., Olszyna, Dariusz P., Claessen, Nike, Opal, Steven M., Weening, Jan J., Van Der Poll, Tom

Journal:

Kidney International

Year:

2001

Language:

english

File:

PDF, 911 KB

english, 2001

41

Inhibition of the release of soluble tumor necrosis factor receptors in experimental endotoxemia by an anti-tumor necrosis factor-αantibody

Jaap Jansen, Tom van der Poll, Marcel Levi, Hugo ten Cate, Harald Gallati, Jan W. ten Cate, Sander J. H. van Deventer

Journal:

Journal of Clinical Immunology

Year:

1995

Language:

english

File:

PDF, 574 KB

english, 1995

42

The influence of corticosteroids on the release of novel biomarkers in human endotoxemia

Martijn D. de Kruif, Lucienne C. Lemaire, Ida A. Giebelen, Joachim Struck, Nils G. Morgenthaler, Jana Papassotiriou, Peter J. Elliott, Tom van der Poll

Journal:

Intensive Care Medicine

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

43

Cecal ligation and puncture induced sepsis impairs host defense againstEnterococcus faeciumperitonitis

Masja Leendertse, Rob J. Willems, Ida A. Giebelen, Sandrine Florquin, Petra S. van den Pangaart, Marc J. Bonten, Tom van der Poll

Journal:

Intensive Care Medicine

Year:

2009

Language:

english

File:

PDF, 321 KB

english, 2009

44

Soluble ST2 plasma concentrations predict mortality in severe sepsis

Jacobien J. Hoogerwerf, Michael W. T. Tanck, Marieke A. D. van Zoelen, Xavier Wittebole, Pierre-François Laterre, Tom van der Poll

Journal:

Intensive Care Medicine

Year:

2010

Language:

english

File:

PDF, 314 KB

english, 2010

45

Systemic versus localized coagulation activation contributing to organ failure in critically ill patients

Marcel Levi, Tom van der Poll, Marcus Schultz

Journal:

Seminars in Immunopathology

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

46

Is the septic response good or bad?

Willem Joost Wiersinga, Tom van der Poll

Journal:

Current Infectious Disease Reports

Year:

2007

Language:

english

File:

PDF, 4.17 MB

english, 2007

47

Differential dose-dependent effects of prednisolone on shedding of endothelial adhesion molecules during human endotoxemia

Lucienne C. Lemaire, Martijn D. de Kruif, Ida A. Giebelen, Marieke A.D. van Zoelen, Cornelis van’t Veer, Tom van der Poll

Journal:

Immunology Letters

Year:

2008

Language:

english

File:

PDF, 293 KB

english, 2008

48

Effect of interleukin 10 on the release of the CXC chemokines growth related oncogene GRO-α and epithelial cell-derived neutrophil activating peptide (ENA)-78 during human endotoxemia

Dariusz P. Olszyna, Dasja Pajkrt, Sander J.H. van Deventer, Tom van der Poll

Journal:

Immunology Letters

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

49

CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats

Petra J.G. Zwijnenburg, Machteld M.J. Polfliet, Sandrine Florquin, Timo K. van den Berg, Christine D. Dijkstra, Sander J.H. van Deventer, John J. Roord, Tom van der Poll, A.Marceline van Furth

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 180 KB

english, 2003

50

Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus

Koenraad F. Van Der Sluijs, Leontine J. R. Van Elden, Ramon Arens, Monique Nijhuis, Rob Schuurman, Sandrine Florquin, Joan Kwakkel, Shizuo Akira, Henk M. Jansen, René Lutter, Tom Van Der Polls

Journal:

Year:

2005

Language:

english

File:

PDF, 277 KB

english, 2005